TB-500 10mg
$35.00
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Buy TB-500 10mg—Thymosin Beta-4 Research Peptide
TB-500 is a synthetic peptide corresponding to the actin-binding domain fragment of Thymosin Beta-4 (TBeta4)—a naturally occurring 43-amino acid protein involved in actin regulation and cellular migration. TB-500 specifically represents the Ac-SDKP fragment that retains the biological activity of full-length Thymosin Beta-4 in research models. Unlike BPC-157, which initiates local vascular repair, TB-500 promotes systemic cell migration and broader tissue remodeling—making them mechanistically complementary research compounds frequently studied together.
TB-500 is available in 10mg lyophilized powder format, independently tested to greater than 99% purity with batch-specific COA. All products are for laboratory research use only.
Classification & Mechanism
TB-500 exerts its research effects through actin regulation—specifically by sequestering G-actin monomers, which influences the actin polymerization dynamics that drive cellular migration. This mechanism places TB-500 in a distinct mechanistic class from angiogenic peptides like BPC-157.
Primary mechanism: G-actin sequestration, modulation of actin polymerization dynamics, enhanced cellular motility
Downstream: Activation of resident progenitor cell populations in tissue repair research models
Vascular contribution: Promotes new blood vessel formation through a mechanism distinct from BPC-157’s VEGFR2 pathway
Distribution pattern: Systemic—TB-500 distributes broadly, complementing BPC-157’s more local activity profile
Research Applications
Systemic cell migration and structural tissue remodeling research
Actin regulation and cytoskeletal reorganization pathway studies
Soft tissue, muscle, and connective tissue repair research models
Cardiovascular tissue repair signaling research
Hair follicle stem cell migration research
Anti-inflammatory signaling pathway studies
Product Specifications
| Compound | TB-500 (Thymosin Beta-4 Actin-Binding Fragment) |
| Also Known As | Thymosin Beta 4, TB4 Fragment, TBeta4 |
| Type | Synthetic peptide - actin-binding domain fragment of Thymosin Beta-4 |
| CAS Number | 885340-08-9 (TB-500 fragment) |
| Molecular Formula | C212H350N56O78S |
| Molecular Weight | 4,963.44 g/mol |
| Form | Lyophilized powder |
| Purity | >99% HPLC Verified - Batch COA Available |
| Available Size | 10mg |
| Storage | Lyophilized: -20°C | Reconstituted: 2-8°C, use within 28 days |
| Reconstitution | Bacteriostatic Water (BAC Water) |
| Intended Use | Research Use Only (RUO) |
Frequently Ask Questions
