KPV 10mg
$30.00
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Buy KPV 10mg – Alpha-MSH Tripeptide Research Peptide
KPV is a synthetic tripeptide representing the C-terminal sequence (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone (alpha-MSH). While the full 13-amino acid alpha-MSH molecule has broad melanocortin receptor activity, the KPV tripeptide retains the anti-inflammatory signaling properties of the parent molecule in a significantly smaller and more stable format. KPV has been studied as a more practical research alternative to full alpha-MSH for investigating melanocortin receptor-mediated anti-inflammatory pathways.
KPV is available in 10mg lyophilized format, independently tested to greater than 99% purity. All products are for laboratory research use only.
Classification & Mechanism
Target receptors: Melanocortin receptors MC1R, MC3R, MC4R – partial agonist activity
Primary studied mechanism: NF-kappaB pathway suppression, reduced pro-inflammatory cytokine production
Secondary: Inhibition of inflammatory cell recruitment signaling
Gut epithelial relevance: Studied for intestinal epithelial cell signaling and inflammatory bowel pathway research
Stability advantage: Tripeptide format provides superior aqueous stability vs full-length alpha-MSH
Research Applications
Melanocortin receptor (MC1R, MC3R, MC4R) interaction studies
NF-kappaB anti-inflammatory pathway research
Gut epithelial and intestinal signaling research
Inflammatory cytokine modulation studies
Comparative alpha-MSH fragment activity research
Product Specifications
| Compound | KPV (Lys-Pro-Val) |
| Full Name | Alpha-MSH C-Terminal Tripeptide (Lysine-Proline-Valine) |
| Type | Synthetic tripeptide - C-terminal fragment of alpha-melanocyte-stimulating hormone |
| Class | Melanocortin Receptor Partial Agonist |
| CAS Number | 66003-58-5 |
| Molecular Formula | C14H26N4O4 |
| Molecular Weight | 314.38 g/mol |
| Form | Lyophilized powder |
| Purity | >99% HPLC Verified - Batch COA Available |
| Available Size | 10mg |
| Storage | Lyophilized: -20°C | Reconstituted: 2-8°C, use within 28 days |
| Reconstitution | Bacteriostatic Water (BAC Water) |
| Intended Use | Research Use Only (RUO) |
Frequently Ask Questions
Is KPV the same as alpha-MSH?
No. KPV is a tripeptide fragment representing only the C-terminal three amino acids (Lys-Pro-Val) of alpha-MSH (which has 13 amino acids). KPV retains the anti-inflammatory signaling properties of ?-MSH but is significantly smaller, more stable in aqueous solution, and has a distinct receptor selectivity profile. KPV acts primarily on MC1R, MC3R, and MC4R as a partial agonist, unlike full ?-MSH which has broader melanocortin system activity including MC2R and MC5R.
Is KPV approved for human use?
No. KPV is sold strictly for laboratory and controlled scientific research purposes only (RUO). Not approved by the FDA or any regulatory authority for human or veterinary use.
