GHK-CU / KPV 60mg
$40.00
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Buy GHK-Cu 50 mg / KPV 10 mg
GHK-Cu 50 mg / KPV 10 mg is a dual-peptide research complex supplied as a research-grade laboratory compound. The formulation contains GHK-Cu and KPV in a defined 50 mg / 10 mg composition for controlled laboratory and analytical research. For research use only. Not intended for human or veterinary use.
GHK-Cu 50 mg / KPV 10 mg
Research Compound Overview
GHK-Cu / KPV combines two distinct tripeptide research compounds in a single formulation: 50 mg GHK-Cu (copper tripeptide-1) and 10 mg KPV (Lys-Pro-Val). The combination provides a platform for investigating extracellular-matrix remodeling, fibroblast activity, oxidative and inflammatory signaling, and cellular responses associated with tissue repair.
Rather than acting through the same pathway, GHK-Cu and KPV have substantially different biological characteristics. This makes the combination particularly relevant to research examining interactions between regenerative/remodeling pathways and inflammatory signaling.
GHK-Cu – Copper Binding & Tissue Remodeling
GHK (glycyl-L-histidyl-L-lysine) is a naturally occurring human tripeptide found in plasma and other biological fluids. It has a strong affinity for copper(II), forming the biologically studied GHK-Cu complex.
Experimental research has associated GHK-Cu with regulation of extracellular-matrix components and tissue-remodeling processes. Studies have reported effects involving collagen and glycosaminoglycan synthesis, fibroblast activity, angiogenesis, antioxidant responses, and matrix metalloproteinase regulation. Animal wound models have also demonstrated increased collagen accumulation and other connective-tissue components following exposure to GHK-Cu.
GHK-Cu has additionally been investigated for modulation of inflammatory signaling. Preclinical studies have reported reductions in inflammatory mediators and effects involving NF-κB and p38 MAPK signaling, although these findings should not be interpreted as established therapeutic effects in humans.
KPV – α-MSH-Derived Research Tripeptide
KPV is the C-terminal tripeptide Lys-Pro-Val derived from α-melanocyte-stimulating hormone (α-MSH).
Despite originating from α-MSH, KPV lacks the conventional melanocortin receptor-binding sequence. Experimental evidence indicates that its anti-inflammatory activity can occur independently of the classical melanocortin receptors, distinguishing it from melanocortin agonists such as Melanotan I and Melanotan II.
KPV has been investigated in experimental inflammatory models involving IL-1β-associated signaling, inflammatory-cell migration, cytokine responses, and related inflammatory pathways. The precise mechanisms responsible for all of KPV’s observed biological effects remain incompletely characterized.
Complementary Research Profile
The GHK-Cu / KPV formulation contains two distinct peptide components in a defined 50 mg / 10 mg composition. The combined product is supplied as a research-grade laboratory compound for controlled research and analytical applications.
Research Applications
• Peptide characterization
• Comparative analytical studies
• Molecular and structural research
• Controlled laboratory research involving peptide compounds
Research Use Only
GHK-Cu 50 mg / KPV 10 mg is intended strictly for laboratory research use. It is not a pharmaceutical product and is not approved for human or veterinary use.
Product Specifications
| Compound | GHK-CU / KPV (Lys-Pro-Val) |
| Type | Synthetic tripeptide - C-terminal fragment of alpha-melanocyte-stimulating hormone |
| Class | Melanocortin Receptor Partial Agonist |
| CAS Number | 66003-58-5 |
| Molecular Formula | C14H26N4O4 |
| Molecular Weight | 314.38 g/mol |
| Form | Lyophilized powder |
| Purity | >99% HPLC Verified - Batch COA Available |
| Available Size | 10mg |
| Storage | Lyophilized: -20°C | Reconstituted: 2-8°C, use within 28 days |
| Reconstitution | Bacteriostatic Water (BAC Water) |
| Intended Use | Research Use Only (RUO) |
Frequently Ask Questions
Is KPV the same as alpha-MSH?
No. KPV is a tripeptide fragment representing only the C-terminal three amino acids (Lys-Pro-Val) of alpha-MSH (which has 13 amino acids). KPV retains the anti-inflammatory signaling properties of ?-MSH but is significantly smaller, more stable in aqueous solution, and has a distinct receptor selectivity profile. KPV acts primarily on MC1R, MC3R, and MC4R as a partial agonist, unlike full ?-MSH which has broader melanocortin system activity including MC2R and MC5R.
Is KPV approved for human use?
No. KPV is sold strictly for laboratory and controlled scientific research purposes only (RUO). Not approved by the FDA or any regulatory authority for human or veterinary use.
