SS-31 50mg
$80.00
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Buy SS-31 50mg (Elamipretide)—Mitochondria-Targeting Research Peptide
SS-31 (also known as Elamipretide, MTP-131, or Bendavia) is a synthetic cell-permeable tetrapeptide that selectively targets the inner mitochondrial membrane. Its unique structure—featuring alternating cationic and aromatic residues—allows it to penetrate cell membranes and accumulate within the inner mitochondrial membrane where it interacts with cardiolipin, a phospholipid critical to mitochondrial function and integrity.
SS-31 is available in 50mg lyophilized format, independently tested to greater than 99% purity. All products are for laboratory research use only.
Classification & Mechanism
SS-31’s mechanism centers on its interaction with cardiolipin—a unique phospholipid almost exclusively found in the inner mitochondrial membrane where it plays essential roles in organizing the respiratory complexes of the electron transport chain.
Target: Cardiolipin in the inner mitochondrial membrane—most specific mitochondrial targeting of any research peptide
ETC function: Supports electron transport chain complex organization and oxidative phosphorylation efficiency
ROS reduction: Reduces mitochondrial reactive oxygen species production in research models
Membrane potential: Studied for effects on mitochondrial membrane potential (DeltaPsim)
Cell permeability: Penetrates cell membranes without requiring active transport
Research Applications
Mitochondrial cardiolipin interaction studies
Electron transport chain function research
Mitochondrial membrane potential research
Cardiac tissue energy metabolism modeling
Oxidative stress and ROS pathway research
Ischemia-reperfusion injury research models
Product Specifications
| Compound | SS-31 (Elamipretide) |
| Also Known As | Elamipretide, MTP-131, Bendavia, D-Arg-2'6'-Dmt-Lys-Phe-NH2 |
| Type | Synthetic cell-permeable tetrapeptide |
| Class | Mitochondria-Targeting Peptide (MTP) |
| CAS Number | 736992-21-5 |
| Molecular Formula | C32H49N7O5 |
| Molecular Weight | 631.78 g/mol |
| Form | Lyophilized powder |
| Purity | >99% HPLC Verified - Batch COA Available |
| Available Size | 50mg |
| Storage | Lyophilized: -20°C | Reconstituted: 2-8°C, use within 28 days |
| Reconstitution | Bacteriostatic Water (BAC Water) |
| Intended Use | Research Use Only (RUO) |
| SEO Action | Fix URL from /product/--31/ to /product/ss-31-50mg/ --31 URL is not indexable |
Frequently Ask Questions
What does SS-31 stand for?
SS refers to Szeto-Schiller - the researchers (Hazel Szeto and Peter Schiller) who developed this class of mitochondria-targeting peptides at Weill Cornell Medical College. The "31" refers to its position in their compound numbering series. The systematic name is D-Arg-2'6'-Dmt-Lys-Phe-NH2 - it contains a D-arginine at the N-terminus and a dimethyltyrosine modification.
Is SS-31 approved for human use?
No. SS-31 (research grade) is sold strictly for laboratory research use only (RUO). Note: Elamipretide (the pharmaceutical version of SS-31) has completed Phase 2 and Phase 3 clinical trials for Barth syndrome and ischemic cardiomyopathy - however it has not received FDA approval as of July 2026. Our SS-31 is research-grade material, not the pharmaceutical compound.
